Researchers developed a single-cell transcriptomic clock that measures aging within specific T cell subsets. Analysis of nearly two million immune cells showed that COVID-19 alters T cell composition ...

In a collaboration between several labs at UNC Lineberger, researchers have defined cancer-associated fibroblast (CAF) subtypes that are clinically robust, prognostic, and predictive of immunotherapy ...

ArgenTag joins PacBio to enable instrument-free single-cell kits to support long-read isoform sequencing at single-cell ...

HER2-positive gastric cancer accounts for a substantial proportion of advanced cases and has long been treated with HER2-targeted therapies. While trastuzumab deruxtecan has shown superior activity ...

Spatial transcriptomics (ST) technologies reveal the spatial organization of gene expression in tissues, providing critical insights into development, neurobiology, and cancer. However, the high cost ...

Immunotherapy—which activates the body's own immune system to kill cancer cells—has not worked well against a rare and fatal ...

Scientists in China have unveiled a breakthrough way to mass-produce powerful cancer-fighting immune cells in the lab. By ...

These findings underscore the promise of single-cell transcriptomic biomarkers to disentangle the systemic and cell-intrinsic components of immune ...

Immune checkpoint inhibitors and other immunotherapies/ cancer vaccines have revolutionised the oncology landscape, offering durable responses in cancers ...